Motor function is the primary driver of the associations of sarcopenia and physical frailty with adverse health outcomes in community-dwelling older adults.

ABSTRACT:

Background

This study tested the hypothesis that sarcopenia and its constituent components, reduced lean muscle mass and impaired motor function, are associated with reduced survival and increased risk of incident disabilities.

Methods

1466 community-dwelling older adults underwent assessment of muscle mass with bioelectrical impedance analysis (BIA), grip strength, gait speed and other components of physical frailty and annual self-report assessments of disability. We used Cox proportional hazards models that controlled for age, sex, race, education and height to examine the associations of a continuous sarcopenia metric with the hazard of death and incident disabilities.

Results

Mean baseline age was about 80 years old and follow-up was 5.5 years. In a proportional

SUBMITTER: Buchman AS 

PROVIDER: S-EPMC7853482 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature