Accessing Olfactory Habituation in Drosophila melanogaster with a T-maze Paradigm.

ABSTRACT: Habituation is the process whereby perceptual changes alter the value of environmental stimuli, enabling salience filtering. This behavioral response decrement is a form of non-associative learning, where the subject learns about the stimulus and does not involve sensory adaptation, sensory or motor fatigue. The range of behavioral responses in D. melanogaster led to the development of a number of habituation paradigms addressing various sensory modalities. Habituation of osmotactic responses has previously been measured with the Y-maze test and required 30 min of odor exposure. Here, we describe an olfactory habituation assay utilizing the widely used in associative learning paradigms T-maze. Continuous or repetitive odor exposure for 4 min is adequate to attenuate osmotactic respo

SUBMITTER: Semelidou O 

PROVIDER: S-EPMC7854066 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature