Characterization of Biological Motion Using Motion Sensing Superpixels.

ABSTRACT: Precise spatiotemporal regulation is the foundation for the healthy development and maintenance of living organisms. All cells must correctly execute their function in the right place at the right time. Cellular motion is thus an important dynamic readout of signaling in key disease-relevant molecular pathways. However despite the rapid advancement of imaging technology, a comprehensive quantitative description of motion imaged under different imaging modalities at all spatiotemporal scales; molecular, cellular and tissue-level is still lacking. Generally, cells move either 'individually' or 'collectively' as a group with nearby cells. Current computational tools specifically focus on one or the other regime, limiting their general applicability. To address this, we recently developed and

SUBMITTER: Zhou FY 

PROVIDER: S-EPMC7854275 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature