Interleukin 15 and Eotaxin correlate with the outcome of breast cancer patients vice versa independent of CTC status.

ABSTRACT:

Background

Circulating tumor cells (CTC) in the peripheral blood in women with breast cancer has been found to be an indicator of prognosis before the start of systemic treatment. The aim of this study is the assessment of specific cytokine profiles as markers for CTC involvement that could act as independent prognostic markers in terms of survival outcome for breast cancer patients.

Methods

Patients selected for this study were defined as women with breast cancer of the SUCCESS study. A total of 200 patients' sera were included in this study, 100 patients being positive for circulating tumor cells (CTC) and 100 patients being CTC negative. The matching criteria were histo-pathological grading, lymph node metastasis, hormone receptor status, TNM classification, and patient s

SUBMITTER: Vilsmaier T 

PROVIDER: S-EPMC7854415 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature