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Burden of Anemia in Chronic Kidney Disease: Beyond Erythropoietin.


ABSTRACT: Anemia is a frequent comorbidity of chronic kidney disease (CKD) and is associated with a considerable burden because of decreased patient health-related quality of life and increased healthcare resource utilization. Based on observational data, anemia is associated with an increased risk of CKD progression, cardiovascular events, and all-cause mortality. The current standard of care includes oral or intravenous iron supplementation, erythropoiesis-stimulating agents, and red blood cell transfusion. However, each of these therapies has its own set of population-specific patient concerns, including increased risk of cardiovascular disease, thrombosis, and mortality. Patients receiving dialysis or those who have concurrent diabetes or high blood pressure may be at greater risk of developing

SUBMITTER: Hanna RM 

PROVIDER: S-EPMC7854472 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature