Older adult participation in cancer clinical trials: A systematic review of barriers and interventions.

ABSTRACT: Cancer is a disease of aging and, as the world's population ages, the number of older persons with cancer is increasing and will make up a growing share of the oncology population in virtually every country. Despite this, older patients remain vastly underrepresented in research that sets the standards for cancer treatments. Consequently, most of what we know about cancer therapeutics is based on clinical trials conducted in younger, healthier patients, and effective strategies to improve clinical trial participation of older adults with cancer remain sparse. For this systematic review, the authors evaluated published studies regarding barriers to participation and interventions to improve participation of older adults in cancer trials. The quality of the available evidence was low and, de

SUBMITTER: Sedrak MS 

PROVIDER: S-EPMC7854940 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature