Imaging reveals distinct textures at three infant skin sites and reflects skin barrier status.

ABSTRACT:

Background

Infant diaper dermatitis (DD) is a prevalent condition due to multiple, interactive factors including increased skin hydration, irritant exposure, and increased skin pH. We examined diaper dermatitis vs within diaper and non-diaper controls over time and characterized the association of skin color and texture relative to skin barrier integrity, hydration, and pH.

Materials and methods

The prospective study included 46 infants with DD at well-child visits. Skin integrity was evaluated over 15 days, including visual skin condition, rate of stratum corneum transepidermal water accumulation, hydration, pH, and skin color and texture from high-resolution digital skin surface images. Effects by site and time were evaluated with general linear models.

Results

Six

SUBMITTER: O Visscher M 

PROVIDER: S-EPMC7854941 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature