Exposure to bisphenols and asthma morbidity among low-income urban children with asthma.

ABSTRACT:

Background

Bisphenol A (BPA) has been linked with pediatric asthma development and allergic airway inflammation in animal models. Whether exposure to BPA or its structural analogs bisphenol S (BPS) and bisphenol F (BPF) is associated with asthma morbidity remains unknown.

Objective

We examined associations between bisphenols and morbidity due to pediatric asthma.

Methods

We quantified concentrations of BPA, BPS, and BPF in 660 urine samples from 148 predominantly low-income, African American children (aged 5-17 years) with established asthma. We used biobanked biospecimens and data on symptoms, health care utilization, and pulmonary function and inflammation that were collected every 3 months over the course of a year. We used generalized estimating equations to exami

SUBMITTER: Quiros-Alcala L 

PROVIDER: S-EPMC7855247 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature