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Predictors of Survival After Liver Transplantation in Patients With the Highest Acuity (MELD ≥40).


ABSTRACT:

Objective

To identify factors that accurately predict 1-year survival for liver transplant recipients with a MELD score ≥40.

Background

Although transplant is beneficial for patients with the highest acuity (MELD ≥40), mortality in this group is high. Predicting which patients are likely to survive for >1 year would be medically and economically helpful.

Methods

The Scientific Registry of Transplant Recipients database was reviewed to identify adult liver transplant recipients from 2002 through 2016 with MELD score ≥40 at transplant. The relationships between 44 recipient and donor factors and 1-year patient survival were examined using random survival forests methods. Variable importance measures were used to identify the factors with the strongest influence on survi

SUBMITTER: Evans MD 

PROVIDER: S-EPMC7855276 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature