Intracranial and Cerebral Perfusion Pressure Thresholds Associated With Inhospital Mortality Across Pediatric Neurocritical Care.

ABSTRACT:

Objectives

Targets for treatment of raised intracranial pressure or decreased cerebral perfusion pressure in pediatric neurocritical care are not well defined. Current pediatric guidelines, based on traumatic brain injury, suggest an intracranial pressure target of less than 20 mm Hg and cerebral perfusion pressure minimum of 40-50 mm Hg, with possible age dependence of cerebral perfusion pressure. We sought to define intracranial pressure and cerebral perfusion pressure thresholds associated with inhospital mortality across a large single-center pediatric neurocritical care cohort.

Design

Retrospective chart review.

Setting

PICU, single quaternary-care center.

Patients

Individuals receiving intracranial pressure monitoring from January 2012 to December 2016.

SUBMITTER: Woods KS 

PROVIDER: S-EPMC7855782 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature