Adding cognitive therapy to antidepressant medications decreases suicidal ideation.

ABSTRACT:

Background

Psychotherapy for depression and antidepressant medications have both been associated with decreases in suicidal ideation. Studies have not examined whether adding psychotherapy to antidepressant medications further reduces suicidal ideation relative to medications alone in adults.

Methods

Participants (N = 452) were randomized to 7 months of treatment with antidepressant medications or combined treatment with both medications and cognitive therapy for depression. We examined change in the suicide items from the Beck Depression Inventory (BDI) and Hamilton Depression Rating Scale (HDRS) across treatment using Bayesian generalized linear mixed models for non-continuous outcomes.

Results

Suicidal ideation decreased across treatment. When measured with the BDI

SUBMITTER: Khazanov GK 

PROVIDER: S-EPMC7855962 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature