Ontology highlight
ABSTRACT:
SUBMITTER: Chen Z
PROVIDER: S-EPMC7856083 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Chen Zuojia Z Luo Jialie J Li Jian J Kim Girak G Stewart Andy A Urban Joseph F JF Huang Yuefeng Y Chen Shan S Wu Ling-Gang LG Chesler Alexander A Trinchieri Giorgio G Li Wei W Wu Chuan C
Immunity 20201120 1
The gastrointestinal tract is known as the largest endocrine organ that encounters and integrates various immune stimulations and neuronal responses due to constant environmental challenges. Enterochromaffin (EC) cells, which function as chemosensors on the gut epithelium, are known to translate environmental cues into serotonin (5-HT) production, contributing to intestinal physiology. However, how immune signals participate in gut sensation and neuroendocrine response remains unclear. Interleuk ...[more]