Moody kids years later: Long-term outcomes of youth from the Omega-3 and therapy (OATS) studies.

ABSTRACT:

Background

This naturalistic follow-up study examines outcomes for youth with depression (n = 25) or subsyndromal bipolar disorder (n = 13) 2-5 years after participation in randomized clinical trials (RCTs) of omega-3 fatty acids (Ω3), individual family psychoeducational psychotherapy (IF-PEP), and their combination METHODS: Forty percent (38/95) of RCT families completed a follow-up assessment RESULTS: Relapse rates and conversion to bipolar disorder were consistent with published literature. Original treatment assignment did not impact current functioning. Overall, participants' mood severity, executive functioning, and global functioning continued to be better than at RCT baseline. Depressive symptoms increased significantly from end of RCT. Manic symptom severity, executive fun

SUBMITTER: Fristad MA 

PROVIDER: S-EPMC7856236 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature