Coming to Consensus: What Defines Deep Partial Thickness Burn Injuries in Porcine Models?

ABSTRACT: Deep partial thickness burns are clinically prevalent and difficult to diagnose. In order to develop methods to assess burn depth and therapies to treat deep partial thickness burns, reliable, accurate animal models are needed. The variety of animal models in the literature and the lack of precise details reported for the experimental procedures make comparison of research between investigators challenging and ultimately affect translation to patients. They sought to compare deep partial thickness porcine burn models from five well-established laboratories. In doing so, they uncovered a lack of consistency in approaches to the evaluation of burn injury depth that was present within and among various models. They then used an iterative process to develop a scoring rubric with an educational

SUBMITTER: Gibson ALF 

PROVIDER: S-EPMC7856457 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature