Spatial and dosimetric evaluation of residual distortions of prostate and seminal vesicle bed after image-guided definitive and postoperative radiotherapy of prostate cancer with endorectal balloon.

ABSTRACT:

Purpose

To quantify daily residual deviations from the planned geometry after image-guided prostate radiotherapy with endorectal balloon and to evaluate their effect on the delivered dose distribution.

Methods

Daily kV-CBCT imaging was used for online setup-correction in six degrees of freedom (6-dof) for 24 patients receiving definitive (12 RT_def patients) or postoperative (12 RT_postop patients) radiotherapy with endorectal balloon (overall 739 CBCTs). Residual deviations were evaluated using several spatial and dosimetric variables, including: (a) posterior Hausdorff distance HD^post (=maximum distance between planned and daily CTV contour), (b) point P_worst with largest HD^post over all fractions, (c) equivalent uniform

SUBMITTER: Levegrun S 

PROVIDER: S-EPMC7856505 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature