Controllable Cell Deformation Using Acoustic Streaming for Membrane Permeability Modulation.

ABSTRACT: Hydrodynamic force loading platforms for controllable cell mechanical deformation play an essential role in modern cell technologies. Current systems require assistance from specific microstructures thus limiting the controllability and flexibility in cell shape modulation, and studies on real-time 3D cell morphology analysis are still absent. This article presents a novel platform based on acoustic streaming generated from a gigahertz device for cell shape control and real-time cell deformation analysis. Details in cell deformation and the restoration process are thoroughly studied on the platform, and cell behavior control at the microscale is successfully achieved by tuning the treating time, intensity, and wave form of the streaming. The application of this platform in cell membrane pe

SUBMITTER: Guo X 

PROVIDER: S-EPMC7856903 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature