Global adaptation complicates the interpretation of genome scans for local adaptation.

ABSTRACT: Spatially varying selection promotes variance in allele frequencies, increasing genetic differentiation between the demes of a metapopulation. For that reason, outliers in the genome-wide distribution of summary statistics measuring genetic differentiation, such as F_ST , are often interpreted as evidence for alleles that contribute to local adaptation. However, theoretical studies have shown that in spatially structured populations the spread of beneficial mutations with spatially uniform fitness effects can also induce transient genetic differentiation. In recent years, numerous empirical studies have suggested that such species-wide, or global, adaptation makes a substantial contribution to molecular evolution. In this perspective, we discuss how commonly such global ad

SUBMITTER: Booker TR 

PROVIDER: S-EPMC7857299 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature