Carbogen inhalation during non-convulsive status epilepticus: A quantitative exploratory analysis of EEG recordings.

ABSTRACT:

Objective

To quantify the effect of inhaled 5% carbon-dioxide/95% oxygen on EEG recordings from patients in non-convulsive status epilepticus (NCSE).

Methods

Five children of mixed aetiology in NCSE were given high flow of inhaled carbogen (5% carbon dioxide/95% oxygen) using a face mask for maximum 120s. EEG was recorded concurrently in all patients. The effects of inhaled carbogen on patient EEG recordings were investigated using band-power, functional connectivity and graph theory measures. Carbogen effect was quantified by measuring effect size (Cohen's d) between "before", "during" and "after" carbogen delivery states.

Results

Carbogen's apparent effect on EEG band-power and network metrics across all patients for "before-during" and "before-after" inhalation com

SUBMITTER: Ramaraju S 

PROVIDER: S-EPMC7857554 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature