Cardiac pacing in severe recurrent reflex syncope and tilt-induced asystole.

ABSTRACT:

Aim

The benefit of cardiac pacing in patients with severe recurrent reflex syncope and asystole induced by tilt testing has not been established. The usefulness of tilt-table test to select candidates for cardiac pacing is controversial.

Methods and results

We randomly assigned patients aged 40 years or older who had at least two episodes of unpredictable severe reflex syncope during the last year and a tilt-induced syncope with an asystolic pause longer than 3 s, to receive either an active (pacing ON; 63 patients) or an inactive (pacing OFF; 64 patients) dual-chamber pacemaker with closed loop stimulation (CLS). The primary endpoint was the time to first recurrence of syncope. Patients and independent outcome assessors were blinded to the assigned treatment. After a median

SUBMITTER: Brignole M 

PROVIDER: S-EPMC7857694 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature