Management of patients with a failed kidney transplant: what should we do?

ABSTRACT: The number of kidney transplant recipients returning to dialysis after graft failure is steadily increasing over time. Patients with a failed kidney transplant have been shown to have a significant increase in mortality compared with patients with a functioning graft or patients initiating dialysis for the first time. Moreover, the risk for infectious complications, cardiovascular disease and malignancy is greater than in the dialysis population due to the frequent maintenance of low-dose immunosuppression, which is required to reduce the risk of allosensitization, particularly in patients with the prospect of retransplantation from a living donor. The management of these patients present several controversial opinions and clinical guidelines are lacking. This article aims to review the le

SUBMITTER: Fiorentino M 

PROVIDER: S-EPMC7857798 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature