Association between tear and blood glucose concentrations: Random intercept model adjusted with confounders in tear samples negative for occult blood.

ABSTRACT:

Aims/introduction

To prevent diabetic complications, strict glucose control and frequent monitoring of blood glucose levels with invasive methods are necessary. We considered the monitoring of tear glucose levels might be a possible method for non-invasive glucose monitoring. To develop tear glucose monitoring for clinical application, we investigated the precise correlation between the blood and tear glucose concentrations.

Materials and methods

A total of 10 participants and 20 participants with diabetes were admitted, and blood and tear samples were collected. Before statistical analysis, we eliminated tear samples contaminated with blood. We observed the daily blood and tear glucose dynamics, and carried out a random intercept model analysis to examine the association be

SUBMITTER: Aihara M 

PROVIDER: S-EPMC7858102 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature