Full-length genome sequencing of a very virulent infectious bursal disease virus isolated in Tunisia.

ABSTRACT: Infectious bursal disease (IBD), an acute, highly contagious, and immunosuppressive avian disease, is caused by infectious bursal disease virus (IBDV) and constitutes one of the main threats to the poultry industry, worldwide. This study was performed to isolate and characterize IBDV isolates circulating in Tunisia. Eleven collected bird samples were identified using an SYBR Green-based one-step real-time reverse transcriptase polymerase chain reaction. The full-length genome sequencing of 7 of the 11 IBDV isolates has been realized. VP2 gene data showed limited sequence variations for all the 7 tested samples. The few nucleotide changes were silent and the deduced amino acid sequences were identical with the exception of a unique and characteristic nonsilent mutation (C₁₂₀₃) de

SUBMITTER: Lachheb J 

PROVIDER: S-EPMC7858174 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature