Material hardship, prefrontal cortex-amygdala structure, and internalizing symptoms in children.

ABSTRACT: Material hardship, or difficulty affording basic resources such as food, housing, utilities, and health care, increases children's risk for internalizing problems. The uncinate fasciculus (UNC) and two of the gray matter regions it connects-the orbitofrontal cortex (OFC) and amygdala-may play important roles in the neural mechanisms underlying these associations. We investigated associations among material hardship, UNC microstructure, OFC and amygdala structure, and internalizing symptoms in children. Participants were 5-9-year-old children (N = 94, 61% female) from socioeconomically diverse families. Parents completed questionnaires assessing material hardship and children's internalizing symptoms. High-resolution, T1-weighted magnetic resonance imaging (n = 51), and diffusion tensor ima

SUBMITTER: Lichtin RD 

PROVIDER: S-EPMC7858699 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature