Gut Microbiota Composition Changes in Constipated Women of Reproductive Age.

ABSTRACT:

Background

Chronic constipation is one of the most prevalent functional gastrointestinal disorders, yet its etiology is multifactorial, and the pathophysiological mechanism is still unclear. Previous studies have shown that the gut microbiota of constipated patients differs from healthy controls; however, many discrepancies exist in the findings, and no clear link has been confirmed between chronic constipation and changes in the gut microbiota. Growing evidence indicates that age, gender, and hormone levels can affect the composition of gut microbiota. The aim of this study is to examine the overall changes in gut microbiota within a specific sub-population of patients, namely, constipated women of reproductive age.

Methods

We carried out a cross-sectional study comparing t

SUBMITTER: Li H 

PROVIDER: S-EPMC7859112 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature