Genome-wide analysis of allele-specific expression of genes in the model diatom Phaeodactylum tricornutum.

ABSTRACT: Recent advances in next generation sequencing technologies have allowed the discovery of widespread autosomal allele-specific expression (aASE) in mammals and plants with potential phenotypic effects. Extensive numbers of genes with allele-specific expression have been described in the diatom Fragilariopsis cylindrus in association with adaptation to external cues, as well as in Fistulifera solaris in the context of natural hybridization. However, the role of aASE and its extent in diatoms remain elusive. In this study, we investigate allele-specific expression in the model diatom Phaeodactylum tricornutum by the re-analysis of previously published whole genome RNA sequencing data and polymorphism calling. We found that 22% of P. tricornutum genes show moderate bias in allelic expression w

SUBMITTER: Hoguin A 

PROVIDER: S-EPMC7859220 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature