Lithium exposure during pregnancy increases fetal growth.

ABSTRACT:

Background

Lithium is an effective treatment in pregnancy and postpartum for the prevention of relapse in bipolar disorder, but there is a lack of knowledge about the potential adverse impact on fetal development.

Aims

To investigate the impact of lithium exposure on early fetal growth.

Methods

In this retrospective observational cohort study, we included all singleton pregnancies of women using lithium and referred for advanced fetal ultrasound scanning between 1994 and 2018 to the University Medical Centers in Leiden and Rotterdam, the Netherlands (n=119). The Generation R study, a population-based cohort, served as a non-exposed control population from the same geographic region (n=8184). Fetal head circumference, abdominal circumference, femur length

SUBMITTER: Poels EM 

PROVIDER: S-EPMC7859661 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature