Computed tomography-measured bone mineral density as a surrogate marker of survival after resection of colorectal liver metastases.

ABSTRACT:

Background

Osteopenia/osteoporosis, characterized by low bone mineral density (BMD), is a potential prognostic factor in cancer patients. We conducted a retrospective single-institution study to evaluate the prognostic impact of preoperative low BMD on colorectal liver metastases (CRLM) in patients undergoing liver resection.

Methods

BMD was assessed in 281 patients undergoing initial liver resection for CRLM by analyzing the preoperative computed tomography (CT) images at the level of the eleventh thoracic vertebra as the region of interest. Survival outcomes were compared between the two groups divided by the median BMD value and prognostic factors after surgery were assessed. Propensity score-based inverse probability weighting (IPW) was applied to adjust for between-grou

SUBMITTER: Ikuta S 

PROVIDER: S-EPMC7859742 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature