Ontology highlight
ABSTRACT:
SUBMITTER: Angala SK
PROVIDER: S-EPMC7859836 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Angala Shiva Kumar SK Joe Maju M McNeil Michael R MR Liav Avraham A Lowary Todd L TL Jackson Mary M
ACS chemical biology 20201231 1
The arabinogalactan of <i>Corynebacterianeae</i> is a critical heteropolysaccharide that tethers outer membrane mycolic acids to peptidoglycan thus forming the characteristic cell wall core of these prokaryotes. An essential α-(1→5)-arabinosyltransferase, AftA, is responsible for the transfer of the first arabinofuranosyl (Ara<i>f</i>) unit of the arabinan domain to the galactan backbone of arabinogalactan, but the number and precise position at which Ara<i>f</i> residue(s) is/are added in mycob ...[more]