Modeling schistosomiasis transmission: the importance of snail population structure.

ABSTRACT:

Background

Schistosomiasis is a neglected tropical disease endemic in 54 countries. A major Schistosoma species, Schistosoma mansoni, is sustained via a life cycle that includes both human and snail hosts. Mathematical models of S. mansoni transmission, used to elucidate the complexities of the transmission cycle and estimate the impact of intervention efforts, often focus primarily on the human host. However, S. mansoni incurs physiological costs in snails that vary with the age of the snail when first infected. Snail demography and the age of snail infection could thus affect the force of infection experienced by humans, which is frequently used to predict the impact of various control strategies.

Methods

To address how these snail host and parasite interactions influence

SUBMITTER: Anderson LC 

PROVIDER: S-EPMC7860629 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature