Development of a method for measuring spleen stiffness by transient elastography using a new device and ultrasound-fusion method.

ABSTRACT:

Background

Hepatic venous pressure gradient (HVPG) is the gold standard index for evaluating portal hypertension; however, measuring HVPG is invasive. Although transient elastography (TE) is the most common procedure for evaluating organ stiffness, accurate measurement of spleen stiffness (SS) is difficult. We developed a device to demonstrate the diagnostic precision of TE and suggest this technique as a valuable new method to measure SS.

Methods

Of 292 consecutive patients enrolled in this single-centre, translational, cross-sectional study from June through September in 2019, 200 underwent SS measurement (SSM) using an M probe (training set, n = 130; inspection set, n = 70). We performed TE with B-mode imaging using an ultrasound-fusion method, printed new devices with a

SUBMITTER: Tanaka T 

PROVIDER: S-EPMC7861355 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature