Serological evidence indicates widespread distribution of rickettsioses in Myanmar.

ABSTRACT:

Background

Little research has been published on the prevalence of rickettsial infections in Myanmar. This study determined the seroprevalence of immunoglobulin G (IgG) antibodies to rickettsial species in different regions of Myanmar.

Methods

Seven hundred leftover blood samples from patients of all ages in primary care clinics and hospitals in seven regions of Myanmar were collected. Samples were screened for scrub typhus group (STG), typhus group (TG) and spotted fever group (SFG) IgG antibodies using enzyme-linked immunosorbent assays (ELISA). Immunofluorescence assays were performed for the same rickettsial groups to confirm seropositivity if ELISA optical density ≥0.5.

Results

Overall IgG seroprevalence was 19% [95% confidence interval (CI) 16-22%] for STG, 5% (

SUBMITTER: Elders PND 

PROVIDER: S-EPMC7862081 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature