Long-term safety of paclitaxel drug-coated balloon-only angioplasty for de novo coronary artery disease: the SPARTAN DCB study.

ABSTRACT:

Objectives

We aimed to investigate long-term survival of paclitaxel DCB for percutaneous coronary intervention (PCI).

Background

Safety concerns have been raised over the use of paclitaxel devices for peripheral artery disease recently, following a meta-analysis suggesting increased late mortality. With regard to drug-coated balloon (DCB) angioplasty for coronary artery intervention however, there is limited data to date regarding possible late mortality relating to paclitaxel.

Methods

We compared all-cause mortality of patients treated with paclitaxel DCB to those with non-paclitaxel second-generation drug-eluting stents (DES) for stable, de novo coronary artery disease from 1st January 2011 till 31st December 2018. To have homogenous groups allowing data on safety t

SUBMITTER: Merinopoulos I 

PROVIDER: S-EPMC7862512 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature