A Role for Extracellular Vesicles in SARS-CoV-2 Therapeutics and Prevention.

ABSTRACT: Extracellular vesicles (EVs) are the common designation for ectosomes, microparticles and microvesicles serving dominant roles in intercellular communication. Both viable and dying cells release EVs to the extracellular environment for transfer of cell, immune and infectious materials. Defined morphologically as lipid bi-layered structures EVs show molecular, biochemical, distribution, and entry mechanisms similar to viruses within cells and tissues. In recent years their functional capacities have been harnessed to deliver biomolecules and drugs and immunological agents to specific cells and organs of interest or disease. Interest in EVs as putative vaccines or drug delivery vehicles are substantial. The vesicles have properties of receptors nanoassembly on their surface. EVs can interact

SUBMITTER: Machhi J 

PROVIDER: S-EPMC7862527 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature