Fibrous bands associated with higher Masaoka stage and poor recurrence-free survival in patients with thymoma.

ABSTRACT:

Background

Fibrous bands (FBs) are one of the histological features in tumors which can be confirmed by hematoxylin and eosin (H&E)-stained slides. FBs have been reported to correlate with malignancy in various tumors. This study aimed to investigate whether the presence of FBs is associated with malignancy in thymoma.

Methods

A total of 123 consecutive patients with thymoma who underwent microscopically complete resections from January 2000 to December 2018 were enrolled into this study. H&E-stained slides of all thymoma patients were re-examined. Study patients were classified into two groups: with FBs (n = 36) and without FBs (n = 87). Clinicopathological characteristics, overall survival (OS), and recurrence-free survival (RFS) were compared between the two groups. Furth

SUBMITTER: Minami K 

PROVIDER: S-EPMC7862782 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature