Prognostic value of eight immune gene signatures in pancreatic cancer patients.

ABSTRACT:

Background

Pancreatic cancer is one of the most common malignant tumors of the digestive tract, and it has a poor prognosis. Traditional methods are not effective to accurately assess the prognosis of patients with pancreatic cancer. Immunotherapy is a new promising approach for the treatment of pancreatic cancer; however, some patients do not respond well to immunotherapy, which may be related to tumor microenvironment regulation. In this study, we use gene expression database to mine important immune genes and establish a prognostic prediction model for pancreatic cancer patients. We hope to provide a feasible method to evaluate the prognosis of pancreatic cancer and provide valuable targets for pancreatic cancer immunotherapy.

Results

We used univariate COX proportional h

SUBMITTER: Wang W 

PROVIDER: S-EPMC7863419 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature