COPD Clinical Control: predictors and long-term follow-up of the CHAIN cohort.

ABSTRACT:

Background

Control in COPD is a dynamic concept that can reflect changes in patients' clinical status that may have prognostic implications, but there is no information about changes in control status and its long-term consequences.

Methods

We classified 798 patients with COPD from the CHAIN cohort as controlled/uncontrolled at baseline and over 5 years. We describe the changes in control status in patients over long-term follow-up and analyze the factors that were associated with longitudinal control patterns and related survival using the Cox hazard analysis.

Results

134 patients (16.8%) were considered persistently controlled, 248 (31.1%) persistently uncontrolled and 416 (52.1%) changed control status during follow-up. The variables significantly associated with p

SUBMITTER: Calle Rubio M 

PROVIDER: S-EPMC7863480 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature