Implementing genomic screening in diverse populations.

ABSTRACT:

Background

Population-based genomic screening has the predicted ability to reduce morbidity and mortality associated with medically actionable conditions. However, much research is needed to develop standards for genomic screening and to understand the perspectives of people offered this new testing modality. This is particularly true for non-European ancestry populations who are vastly underrepresented in genomic medicine research. Therefore, we implemented a pilot genomic screening program in the BioMe Biobank in New York City, where the majority of participants are of non-European ancestry.

Methods

We initiated genomic screening for well-established genes associated with hereditary breast and ovarian cancer syndrome (HBOC), Lynch syndrome (LS), and familial hypercholester

SUBMITTER: Abul-Husn NS 

PROVIDER: S-EPMC7863616 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature