Trends in Discard of Kidneys from Hepatitis C Viremic Donors in the United States.

ABSTRACT:

Background and objectives

Kidneys from hepatitis C virus (HCV) viremic donors have become more commonly accepted for transplant, especially after effective direct-acting antiviral therapy became available in 2014. We examined the contemporary trend of kidney discard from donors with HCV seropositivity and viremia.

Design, setting, participants, & measurements

Data from the Organ Procurement and Transplantation Network were used to identify deceased donor kidneys recovered for transplant. The exposure was donor HCV antibody status in the first analyses, and donor HCV antibody and viremia status in the second analyses. Multilevel, multivariable logistic regression was used to assess the association of these HCV exposure measures with kidney discard, adjusted for donor characte

SUBMITTER: Chang SH 

PROVIDER: S-EPMC7863640 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature