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Towards Rational Biosurfactant Design-Predicting Solubilization in Rhamnolipid Solutions.


ABSTRACT: The efficiency of micellar solubilization is dictated inter alia by the properties of the solubilizate, the type of surfactant, and environmental conditions of the process. We, therefore, hypothesized that using the descriptors of the aforementioned features we can predict the solubilization efficiency, expressed as molar solubilization ratio (MSR). In other words, we aimed at creating a model to find the optimal surfactant and environmental conditions in order to solubilize the substance of interest (oil, drug, etc.). We focused specifically on the solubilization in biosurfactant solutions. We collected data from literature covering the last 38 years and supplemented them with our experimental data for different biosurfactant preparations. Evolutionary algorithm (EA) and kernel support ve

SUBMITTER: Klosowska-Chomiczewska IE 

PROVIDER: S-EPMC7864340 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature