Clinical Differences between Early- and Late-Onset Asthma: A Population-Based Cross-Sectional Study.

ABSTRACT:

Background

Limited information exists about the nature of late-onset asthma (LOA) without medication intervention when compared to early-onset asthma (EOA). Our goal was to understand how EOA and LOA affect clinical and pathophysiological features.

Methods

A population-based cross-sectional study was carried out in Zhongshan Hospital (Shanghai, China). EOA and LOA were based on age of diagnosis (before and after age 40 years, respectively). Clinical variables were collected with an emphasis on allergic features, analyzed, related, and compared using one-way ANOVA or Kruskal-Wallis test. Correlations between blood basophils and clinical data were evaluated by Spearman's rank test. Statistical analyses were conducted with SPSS v24.0.

Results

Of a total of 12,760 adults

SUBMITTER: Li J 

PROVIDER: S-EPMC7864752 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature