Family history of type 2 diabetes and characteristics of children with newly diagnosed type 1 diabetes.

ABSTRACT:

Aims/hypothesis

Shared aetiopathogenetic factors have been proposed in type 1 diabetes and type 2 diabetes and both diseases have been shown to cluster in families. Characteristics related to type 2 diabetes have been described in patients with type 1 diabetes with a positive family history of type 2 diabetes. We wanted to characterise the family history of type 2 diabetes and its possible effects on the phenotype and genotype of type 1 diabetes in affected children at diagnosis.

Methods

A total of 4993 children under the age of 15 years with newly diagnosed type 1 diabetes from the Finnish Pediatric Diabetes Register were recruited (56.6% boys, median age of 8.2 years) for a cross-sectional, observational, population-based investigation. The family history of diabetes at di

SUBMITTER: Parkkola A 

PROVIDER: S-EPMC7864815 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature