Ontology highlight
ABSTRACT:
SUBMITTER: Normington C
PROVIDER: S-EPMC7864922 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
NPJ biofilms and microbiomes 20210205 1
C. difficile infection (CDI) is a worldwide healthcare problem with ~30% of cases failing primary therapy, placing a burden on healthcare systems and increasing patient morbidity. We have little understanding of why these therapies fail. Here, we use a clinically validated in vitro gut model to assess the contribution of biofilms towards recurrent disease and to investigate biofilm microbiota-C. difficile interactions. Initial experiments show that C. difficile cells became associated with the c ...[more]