Effects of a 1-Year Physical Activity Intervention on Markers of Hemostasis among Breast Cancer Survivors: A Randomized Controlled Trial.

ABSTRACT: Introduction  Physical activity may reduce the development of breast cancer. Whereas hypercoagulability has been linked to adverse outcomes in breast cancer patients, the effects of physical activity on their hemostatic factors are unknown. The study aimed to assess whether long-term (1 year) physical activity can affect hemostatic factors in breast cancer patients. Methods  Fifty-five women (35-75 years) with invasive breast cancer stage I/II were randomized to a physical activity intervention ( n  = 29) lasting 1 year or to a control group ( n  = 26), and analyzed as intention to treat. Fibrinogen, factor VII antigen, tissue factor pathway inhibitor, and von Willebrand factor (VWF) antigen as well as prothrombin fragment 1 + 2, the endogenous thrombin potentia

SUBMITTER: Bohn SK 

PROVIDER: S-EPMC7867414 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature