Effects of intact and hydrolysed blue whiting proteins on blood pressure and markers of kidney function in obese Zucker fa/fa rats.

ABSTRACT:

Purpose

To investigate the effects of diets containing intact or hydrolysed proteins from blue whiting (Micromesistius poutassou) on the development of high blood pressure and markers of kidney function in obese Zucker fa/fa rats which are prone to develop hypertension and renal failure.

Methods

Male rats were fed isocaloric diets containing either intact blue whiting whole meal (BW-WM), blue whiting protein hydrolysate prepared with Alcalase^® (BW-HA) or blue whiting protein hydrolysate prepared with Protamex^® (BW-HP) as 1/3 of total protein with the remaining 2/3 as casein, or casein as sole protein source (control group). Blood pressure was measured at Day 0 and Day 32. Rats were housed in metabolic cages for 24 h for collection of urine in week 4. Af

SUBMITTER: Drotningsvik A 

PROVIDER: S-EPMC7867508 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature