Spot urine iodine levels below the WHO recommendation are not related to impaired thyroid function in healthy children and adolescents.

ABSTRACT:

Purpose

Iodine deficiency in childhood and adolescence may lead to later thyroid dysfunction, stunted growth and cognitive impairment. The World Health Organization (WHO) has issued recommended age-dependent urine iodine concentration targets, but a critical threshold beyond which clinical sequelae are to be expected remains undefined. Our study aimed to investigate spot urine iodine concentration in a typical Central European cohort of children and adolescents, and consider the implications of these values in regard to laboratory parameters for evaluating thyroid function.

Methods

Using the Sandell-Kolthoff method, spot urine iodine concentration was measured cross-sectionally from 1802 healthy children and adolescent in the age range of 0.25-18 years within the LIFE-Child

SUBMITTER: Wallborn T 

PROVIDER: S-EPMC7867514 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature