Multivariate Patterns of Brain-Behavior-Environment Associations in the Adolescent Brain and Cognitive Development Study.

ABSTRACT:

Background

Adolescence is a critical developmental stage. A key challenge is to characterize how variation in adolescent brain organization relates to psychosocial and environmental influences.

Methods

We used canonical correlation analysis to discover distinct patterns of covariation between measures of brain organization (brain morphometry, intracortical myelination, white matter integrity, and resting-state functional connectivity) and individual, psychosocial, and environmental factors in a nationally representative U.S. sample of 9623 individuals (aged 9-10 years, 49% female) participating in the Adolescent Brain and Cognitive Development (ABCD) study.

Results

These analyses identified 14 reliable modes of brain-behavior-environment covariation (canonical r_d

SUBMITTER: Modabbernia A 

PROVIDER: S-EPMC7867576 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature