Relationship between intraoperative measured parameters of parathyroid gland and pathological patterns in patients with secondary hyperparathyroidism.

ABSTRACT:

Background

The hyperplastic patterns of parathyroid glands (PTGs) in secondary hyperparathyroidism (SHPT) are critical for surgical indication and deciding on the approach. Earlier histopathological investigations have suggested the occurrence of an initial increase in the parathyroid cells, with a normal lobular structure (diffuse hyperplasia, DH). After this, the PTGs become hyperplastic with some nodules (nodular hyperplasia, NH). The current study aimed to explore the relationship between the intraoperative measurements of weight, volume, and maximal diameter of dissected PTGs and the histopathological diagnosis of SHPT patients with end-stage renal disease.

Methods

A total of 182 SHPT patients who received parathyroidectomy (PTX) were retrospectively enrolled. Altogethe

SUBMITTER: Sun X 

PROVIDER: S-EPMC7867874 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature