Oral atenolol treatment for infantile hemangiomas: clinical analysis of 133 consecutive patients.

ABSTRACT:

Background

Infantile hemangiomas (IHs) are the most frequently occurring pediatric lesions. Oral propranolol has been shown to be safe and effective in infants with IHs. Side effects such as sleep disturbances have been associated with propranolol. Atenolol is a hydrophilic, selective β1-blocker and therefore may be not associated with side effects attributable to β2-adrenergic receptor blockade and lipophilicity. However, the efficacy of atenolol in the treatment of IHs is poorly understood. The aim of this study was to evaluate the efficacy of atenolol in the treatment of proliferating IHs in a clinical cohort including 133 consecutive patients.

Methods

In this study, we enrolled 133 patients diagnosed as proliferating IHs from the routine clinical and referral practices o

SUBMITTER: Zhao ZL 

PROVIDER: S-EPMC7867894 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature