Intranasal drugs for analgesia and sedation in children admitted to pediatric emergency department: a narrative review.

ABSTRACT: Acute pain is one of the most common symptoms in children admitted to the Pediatric Emergency Department (PED) and its management represents a real clinical challenge for pediatricians. Different painful procedures can be very stressful for young children and their perception of pain can be enhanced by emotional factors, such as anxiety, distress, or anger. Adequate procedural sedation reduces anxiety and emotional trauma for the patient, but it reduces also stress for operators and the time for procedures. We have reviewed the literature on this topic and the drugs covered in these papers were: midazolam, fentanyl, ketamine, and dexmedetomidine. There are several routes of administering for these drugs to provide analgesia and anxiolysis to children: oral, parenteral, or intranasal (IN).

SUBMITTER: Pansini V 

PROVIDER: S-EPMC7867955 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature