DNA Rchitect: an R based visualizer for network analysis of chromatin interaction data.

ABSTRACT:

Motivation

Visualization of multiple genomic data generally requires the use of public or commercially hosted browsers. Flexible visualization of chromatin interaction data as genomic features and network components offer informative insights to gene expression. An open source application for visualizing HiC and chromatin conformation-based data as 2D-arcs accompanied by interactive network analyses is valuable.

Results

DNA Rchitect is a new tool created to visualize HiC and chromatin conformation-based contacts at high (Kb) and low (Mb) genomic resolutions. The user can upload their pre-filtered HiC experiment in bedpe format to the DNA Rchitect web app that we have hosted or to a version they themselves have deployed. Using DNA Rchitect, the uploaded data allows the user t

SUBMITTER: Ramirez RN 

PROVIDER: S-EPMC7867998 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature